Programming of an Arduino control unit for Cell Culture Incubation Chamber

• Main Author: Lim, Ding Yan
• Other Authors: Pui Tze Sian
• Format: Final Year Project
• Language: English
• Published: 2018
• Subjects: DRNTU::Engineering::Bioengineering
• Online Access: http://hdl.handle.net/10356/75185
• Institution: Nanyang Technological University

Today, the problems faced by researchers include the cost associated with recalls of drugs which have side effects went undetected and lacked effective and low-cost model systems to analyse them further. Three-dimensional (3D) tissue models offer more effective and robust pre-clinical screening as compared to two-dimensional (2D) tissue models which are relatively lower in cost and shorter time to cultivate. Devices currently available on the market are not able to handle drug perfusion at cell-viable conditions for long-term testing and imaging experiments at a lower cost. This paper suggests building a portable microcontroller to integrate with portable incubator enclosure for cell experiments and drug screening of three-dimensional (3D) tissue models, presenting a useful diagnostic tool for screening cost-effectively. The portable microcontroller must be able to regulate consistent environment for cell experiments to perform long-term testing and imaging without any disruption to cell viability.