Characterization of structures and interactions of beta 2 integrin tail with cytosolic proteins

• Main Author: Lu, Lewis Zhiping
• Other Authors: Surajit Bhattacharyya
• Format: Theses and Dissertations
• Language: English
• Published: 2018
• Subjects: DRNTU::Science::Biological sciences::Microbiology
• Online Access: http://hdl.handle.net/10356/75223
• Institution: Nanyang Technological University

Integrins are important transmembrane proteins that facilitate many vital processes in humans such as development, immune responses and blood clotting. Extracellular domains of integrin bind to ligands such as the ECM and to other cells while intra-cellularly, cytoplasmic tail domains interact with...