Systematic evaluation of CRISPR-Cas systems reveals higher efficiency of Cpf1 nucleases in HDR-mediated precise genome editing

Background: CRISPR/Cas has the advantages of low cost, easy production, rapid and high efficiency, and low off-target rate. It has quickly become popular in laboratories around the world, and has become an effective tool in scientific research, medical care, and other fields. One of the hottest tech...

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Bibliographic Details
Main Author: Xing, Heyun
Other Authors: Tan Meng How
Format: Theses and Dissertations
Language:English
Published: 2018
Subjects:
Online Access:http://hdl.handle.net/10356/75292
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Institution: Nanyang Technological University
Language: English