Structural and biochemical study of kindlin-3 in integrin activation

Kindlin-3, a member of the FERM family proteins, functions as an adaptor between cell membrane and cytoskeleton proteins. It is mostly expressed in hematopoietic and endothelial cells. Leukocyte adhesion deficiency syndrome (LAD-III) in human has been linked to the expression of mutant Kindlin-3 pro...

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Bibliographic Details
Main Author: Bu, Wenting
Other Authors: Gao Yonggui
Format: Theses and Dissertations
Language:English
Published: 2018
Subjects:
Online Access:http://hdl.handle.net/10356/75441
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Institution: Nanyang Technological University
Language: English
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