Evaluation of stat-modifying small molecules for mediating macrophage polarization
Contact with biomaterials has been shown to induce macrophage polarization towards the pro-inflammatory M1 and anti-inflammatory M2 phenotypes, with implications on clinical outcomes of the affected device. Recent studies suggest STAT1 and STAT3 activation of the JAK/STAT signaling pathway to have c...
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Format: | Final Year Project |
Language: | English |
Published: |
2018
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Online Access: | http://hdl.handle.net/10356/75462 |
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Institution: | Nanyang Technological University |
Language: | English |