Evaluation of stat-modifying small molecules for mediating macrophage polarization

• المؤلف الرئيسي: Salim, Arief Tjitra
• مؤلفون آخرون: Xu Chenjie
• التنسيق: Final Year Project
• اللغة: English
• منشور في: 2018
• الموضوعات: DRNTU::Engineering::Bioengineering
• الوصول للمادة أونلاين: http://hdl.handle.net/10356/75462

Contact with biomaterials has been shown to induce macrophage polarization towards the pro-inflammatory M1 and anti-inflammatory M2 phenotypes, with implications on clinical outcomes of the affected device. Recent studies suggest STAT1 and STAT3 activation of the JAK/STAT signaling pathway to have c...