Evaluation of stat-modifying small molecules for mediating macrophage polarization

Contact with biomaterials has been shown to induce macrophage polarization towards the pro-inflammatory M1 and anti-inflammatory M2 phenotypes, with implications on clinical outcomes of the affected device. Recent studies suggest STAT1 and STAT3 activation of the JAK/STAT signaling pathway to have c...

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Bibliographic Details
Main Author: Salim, Arief Tjitra
Other Authors: Xu Chenjie
Format: Final Year Project
Language:English
Published: 2018
Subjects:
Online Access:http://hdl.handle.net/10356/75462
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Institution: Nanyang Technological University
Language: English