Design of novel F-ATP synthase inhibitors of mycobacterium tuberculosis
F1FO ATP synthase of Mycobacterium tuberculosis is an attractive and intensively-studied drug target. Adenosine triphosphate (ATP) is necessary for cell growth and is vital for cell survival, especially in the case of dormant Mycobacterium. In 2012, an inhibitor of F1FO ATP synthase, Bedaquiline (BD...
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| 格式: | Theses and Dissertations |
| 語言: | English |
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2018
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| 在線閱讀: | http://hdl.handle.net/10356/75829 |
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| 機構: | Nanyang Technological University |
| 語言: | English |