Intracellular delivery of antibiotics to methicillin-resistant Staphylococcus aureus (MRSA) – infected macrophages and keratinocytes

• Main Author: Chow, Yao Xiang
• Other Authors: Loo Say Chye Joachim
• Format: Final Year Project
• Language: English
• Published: 2019
• Subjects: DRNTU::Engineering::Materials::Biomaterials
• Online Access: http://hdl.handle.net/10356/76743
• Institution: Nanyang Technological University

Methicillin-resistant Staphylococcus aureus (MRSA) can invade and survive in mammalian host cells, causing persistent and recurrent infections. Although vancomycin and gentamicin are potent against active extracellular MRSA, they are not effective against intracellular MRSA due to the low cellular u...