Antibiotic potentiators and delivery to persisters

• Main Author: Li, Wenrui
• Other Authors: Loo Say Chye Joachim
• Format: Final Year Project
• Language: English
• Published: 2019
• Subjects: DRNTU::Engineering::Materials::Biomaterials
• Online Access: http://hdl.handle.net/10356/76754
• Institution: Nanyang Technological University

Bacterial persisters are cells that transiently withstand the lethal effects of antibiotic therapy without acquiring genetic mutations. It is increasingly clear that the presence of persisters accounts for the recalcitrance and relapses of chronic bacterial infections and has also been associated wi...