Preparation of model membrane system containing ceramide 6 and their membrane characteristics
In this study, the formation of liposomes containing ceramide and their liposomal membrane characteristics were investigated. Liposomes composed of Ceramide 6 and 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) were examined by varying the amount of ceramide 6 present. The effects of Ceramide 6...
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| Format: | Final Year Project |
| Language: | English |
| Published: |
2019
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| Subjects: | |
| Online Access: | http://hdl.handle.net/10356/76883 |
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| Institution: | Nanyang Technological University |
| Language: | English |
| Summary: | In this study, the formation of liposomes containing ceramide and their liposomal membrane characteristics were investigated. Liposomes composed of Ceramide 6 and 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) were examined by varying the amount of ceramide 6 present. The effects of Ceramide 6 on the liposome formation, dispersibility, permeability, and phase transition temperature were investigated by a fluorescence polarization method, dynamic light scattering (DLS) method, a differential scanning calorimetry (DSC) and small angle X-ray scattering (SAXS). |
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