Detecting somatic mutations in UK Parkinson's disease patient brain samples using whole exome sequencing (WES)

• Main Author: Mok, Chin Yi
• Other Authors: Foo Jia Nee
• Format: Final Year Project
• Language: English
• Published: 2019
• Subjects: Science::Biological sciences::Genetics
• Online Access: http://hdl.handle.net/10356/78856
• Institution: Nanyang Technological University

Parkinson’s disease is a neurological disorder mainly caused by the depletion of dopaminergic neuronal cells in the substantia nigra, which is often the main site of pathogenesis. Although it has affected many patients worldwide over the years, mechanisms underlying neuronal loss remained largely un...