Structure of a conserved Golgi complex-targeting signal in coronavirus envelope proteins

• Main Authors: Li, Yan, Surya, Wahyu, Claudine, Stephanie, Torres, Jaume
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2015
• Subjects: DRNTU::Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/79405; http://hdl.handle.net/10220/25655
• Institution: Nanyang Technological University

Coronavirus envelope (CoV E) proteins are ∼100-residue polypeptides with at least one channel-forming α-helical transmembrane (TM) domain. The extramembrane C-terminal tail contains a completely conserved proline, at the center of a predicted β-coil-β motif. This hydrophobic motif has been reported...