Hybrid method for fast Monte Carlo simulation of diffuse reflectance from a multilayered tissue model with tumor-like heterogeneities
We present a hybrid method that combines a multilayered scaling method and a perturbation method to speed up the Monte Carlo simulation of diffuse reflectance from a multilayered tissue model with finite-size tumor-like heterogeneities. The proposed method consists of two steps. In the first st...
Saved in:
| Main Authors: | , |
|---|---|
| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
2013
|
| Online Access: | https://hdl.handle.net/10356/79476 http://hdl.handle.net/10220/10168 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Institution: | Nanyang Technological University |
| Language: | English |
| Summary: | We present a hybrid method that combines a multilayered
scaling method and a perturbation method to
speed up the Monte Carlo simulation of diffuse reflectance
from a multilayered tissue model with finite-size tumor-like
heterogeneities. The proposed method consists of two steps.
In the first step, a set of photon trajectory information generated
from a baseline Monte Carlo simulation is utilized to
scale the exit weight and exit distance of survival photons for
the multilayered tissue model. In the second step, another
set of photon trajectory information, including the locations
of all collision events from the baseline simulation and the
scaling result obtained from the first step, is employed by the
perturbation Monte Carlo method to estimate diffuse reflectance
from the multilayered tissue model with tumor-like
heterogeneities. Our method is demonstrated to shorten
simulation time by several orders of magnitude. Moreover,
this hybrid method works for a larger range of probe configurations
and tumor models than the scaling method or the
perturbation method alone. |
|---|