LIR motif-containing hyperdisulfide β-ginkgotide is cytoprotective, adaptogenic, and scaffold-ready

• Main Authors: Dutta, Bamaprasad, Huang, Jiayi, To, Janet, Tam, James P.
• 其他作者: School of Biological Sciences
• 格式: Article
• 語言: English
• 出版: 2019
• 主題: Science::Biological sciences; Adaptogenic; Autophagy
• 在線閱讀: https://hdl.handle.net/10356/79519; http://hdl.handle.net/10220/49718

Grafting a bioactive peptide onto a disulfide-rich scaffold is a promising approach to improve its structure and metabolic stability. The ginkgo plant-derived β-ginkgotide β-gB1 is a highly unusual molecule: Small, hyperdisulfide, and found only in selected ancient plants. It also contains a conserv...