Age-related differences in functional connectivity during scene encoding

The functional network underlying episodic encoding involves both the prefrontal cortex (PFC) and medial temporal lobe (MTL).1 Episodic encoding differs in terms of the stimuli and the types of encoding.2. Past neuroimaging studies have found both the parahippocampus in the MTL and inferior frontal...

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Main Author: Leow, Dayton Wei Yang
Other Authors: Chen Shen-Hsing Annabel
Format: Student Research Poster
Language:English
Published: 2014
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Online Access:https://hdl.handle.net/10356/79544
http://hdl.handle.net/10220/24239
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-795442020-09-27T20:30:54Z Age-related differences in functional connectivity during scene encoding Leow, Dayton Wei Yang Chen Shen-Hsing Annabel School of Humanities and Social Sciences Relational encoding Scenes The functional network underlying episodic encoding involves both the prefrontal cortex (PFC) and medial temporal lobe (MTL).1 Episodic encoding differs in terms of the stimuli and the types of encoding.2. Past neuroimaging studies have found both the parahippocampus in the MTL and inferior frontal gyrus (IFG) in the PFC to be activated for scene encoding.3 In addition, when scenes are encoded based on its meaningfulness (i.e. relational encoding), the hippocampus will be activated for relational binding of the stimuli.4. In general, there is converging support for both the IFG and MTL (hippocampus/parahippocampus) to be functionally connected and work in tandem during relational encoding of scenes. Older adults performing relational encoding5 and scene encoding3 exhibited increased inferior frontal activation than young adults to meet their increased cognitive demand. Specifically, an increased inferior frontal activity was shown to compensate for the decreased medial temporal activity.3. The posterior-to-anterior shift in aging (PASA) model6 could potentially be used to account for this medial temporal-to-inferior frontal compensatory shift in brain activation. Although past studies have examined age-related differences in both the IFG and MTL activation during relational encoding of scenes, the IFG-MTL co-activation is not specifically investigated. Hence, this study utilized a functional MRI (fMRI) task sensitive to relational encoding of scenes to evaluate age-related differences in the IFG-MTL functional connectivity (FC). [1st Award] 2014-11-25T07:38:18Z 2019-12-06T13:27:56Z 2014-11-25T07:38:18Z 2019-12-06T13:27:56Z 2014 2014 Student Research Poster Leow, D. W. Y. (2014, March). Age-related differences in functional connectivity during scene encoding. Presented at Discover URECA @ NTU poster exhibition and competition, Nanyang Technological University, Singapore. https://hdl.handle.net/10356/79544 http://hdl.handle.net/10220/24239 en © 2014 The Author(s). application/pdf
institution Nanyang Technological University
building NTU Library
country Singapore
collection DR-NTU
language English
topic Relational encoding
Scenes
spellingShingle Relational encoding
Scenes
Leow, Dayton Wei Yang
Age-related differences in functional connectivity during scene encoding
description The functional network underlying episodic encoding involves both the prefrontal cortex (PFC) and medial temporal lobe (MTL).1 Episodic encoding differs in terms of the stimuli and the types of encoding.2. Past neuroimaging studies have found both the parahippocampus in the MTL and inferior frontal gyrus (IFG) in the PFC to be activated for scene encoding.3 In addition, when scenes are encoded based on its meaningfulness (i.e. relational encoding), the hippocampus will be activated for relational binding of the stimuli.4. In general, there is converging support for both the IFG and MTL (hippocampus/parahippocampus) to be functionally connected and work in tandem during relational encoding of scenes. Older adults performing relational encoding5 and scene encoding3 exhibited increased inferior frontal activation than young adults to meet their increased cognitive demand. Specifically, an increased inferior frontal activity was shown to compensate for the decreased medial temporal activity.3. The posterior-to-anterior shift in aging (PASA) model6 could potentially be used to account for this medial temporal-to-inferior frontal compensatory shift in brain activation. Although past studies have examined age-related differences in both the IFG and MTL activation during relational encoding of scenes, the IFG-MTL co-activation is not specifically investigated. Hence, this study utilized a functional MRI (fMRI) task sensitive to relational encoding of scenes to evaluate age-related differences in the IFG-MTL functional connectivity (FC). [1st Award]
author2 Chen Shen-Hsing Annabel
author_facet Chen Shen-Hsing Annabel
Leow, Dayton Wei Yang
format Student Research Poster
author Leow, Dayton Wei Yang
author_sort Leow, Dayton Wei Yang
title Age-related differences in functional connectivity during scene encoding
title_short Age-related differences in functional connectivity during scene encoding
title_full Age-related differences in functional connectivity during scene encoding
title_fullStr Age-related differences in functional connectivity during scene encoding
title_full_unstemmed Age-related differences in functional connectivity during scene encoding
title_sort age-related differences in functional connectivity during scene encoding
publishDate 2014
url https://hdl.handle.net/10356/79544
http://hdl.handle.net/10220/24239
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