The potential for a controlled human infection platform in Singapore

• Main Authors: Balasingam, Shobana, Horby, Peter, Wilder-Smith, Annelies
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2014
• Subjects: DRNTU::Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/79663; http://hdl.handle.net/10220/24086
• Institution: Nanyang Technological University

For over 100 years, controlled human infection (CHI) studies have been performed to advance the understanding of the pathogenesis, treatment and prevention of infectious diseases. This methodology has seen a resurgence, as it offers an efficient model for selecting the most promising agents for furt...