Excessive sensitivity to uncertain visual input in L-DOPA-induced dyskinesias in Parkinson’s disease : further implications for cerebellar involvement

• Main Authors: Stevenson, James K. R., Lee, Chonho, Lee, Bu-Sung, TalebiFard, Pouria, Ty, Edna, Aseeva, Kristina, Oishi, Meeko M. K., McKeown, Martin J.
• Other Authors: School of Computer Engineering
• Format: Article
• Language: English
• Published: 2014
• Subjects: DRNTU::Science::Medicine
• Online Access: https://hdl.handle.net/10356/79682; http://hdl.handle.net/10220/20322
• Institution: Nanyang Technological University

When faced with visual uncertainty during motor performance, humans rely more on predictive forward models and proprioception and attribute lesser importance to the ambiguous visual feedback. Though disrupted predictive control is typical of patients with cerebellar disease, sensorimotor deficits as...