Sample loading and retrieval by centrifugation in a closed-loop PCR microchip

• Main Authors: Lok, Khoi Seng, Kwok, Yien Chian, Nguyen, Nam-Trung
• Other Authors: School of Mechanical and Aerospace Engineering
• Format: Article
• Language: English
• Published: 2012
• Subjects: DRNTU::Engineering::Computer science and engineering::Computer applications::Computer-aided engineering
• Online Access: https://hdl.handle.net/10356/79770; http://hdl.handle.net/10220/7686
• Institution: Nanyang Technological University

We report on a novel concept of sample loading for microfluidic devices using a benchtop centrifuge and a magnetically actuated circular closed-loop PCR microchip as a model system. The PCR mixture and the ferrofluid were loaded into a specially designed microchip. The microchip was then placed in a...