Co-delivery of drugs and DNA from cationic core–shell nanoparticles self-assembled from a biodegradable copolymer

• Main Authors: Wang, Yong, Gao, Shujun, Ye, Wen-Hui, Yoon, Ho Sup, Yang, Yi-Yan
• Other Authors: School of Biological Sciences
• Format: Article
• Published: 2012
• Subjects: DRNTU::Science::Biological sciences::Genetics
• Online Access: https://hdl.handle.net/10356/79958; http://hdl.handle.net/10220/8737
• Institution: Nanyang Technological University

Non-viral gene-delivery systems are safer to use and easier to produce than viral vectors, but their comparatively low transfection efficiency has limited their applications. Co-delivery of drugs and DNA has been proposed to enhance gene expression or to achieve the synergistic/combined effect of dr...