Benchmarking human protein complexes to investigate drug-related systems and evaluate predicted protein complexes

• Main Authors: Wu, Min, Yu, Qi, Li, Xiaoli, Zheng, Jie, Huang, Jing-Fei, Kwoh, Chee Keong
• Other Authors: School of Computer Engineering
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Engineering::Computer science and engineering
• Online Access: https://hdl.handle.net/10356/80018; http://hdl.handle.net/10220/11909
• Institution: Nanyang Technological University

Protein complexes are key entities to perform cellular functions. Human diseases are also revealed to associate with some specific human protein complexes. In fact, human protein complexes are widely used for protein function annotation, inference of human protein interactome, disease gene predictio...