Age specific differences in efficacy and safety for the CYD-tetravalent dengue vaccine

• Main Authors: Wilder-Smith, Annelies, Massad, Eduardo
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2016
• Subjects: Dengue; Vaccine; Efficacy; Age indication
• Online Access: https://hdl.handle.net/10356/80254; http://hdl.handle.net/10220/40437
• Institution: Nanyang Technological University

CYD-TDV is the first dengue vaccine to have completed Phase 3 efficacy trials. Efficacy was consistently higher in those aged 9 and above for all variables studied: efficacy against virologically confirmed dengue of any severity and serotype, serotype specific efficacy, efficacy dependent on baselin...