The immune response to 6-monthly versus annual standard dose inactivated trivalent influenza vaccination in older people: study protocol for a randomised clinical trial

• Main Authors: Young, Barnaby, Sadarangani, Sapna, Yew, Haur Sen, Yung, Chee Fu, Leo, Yee Sin, Chen, Mark I-Cheng, Wilder-Smith, Annelies
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2017
• Subjects: Influenza; Vaccine
• Online Access: https://hdl.handle.net/10356/80335; http://hdl.handle.net/10220/42142
• Institution: Nanyang Technological University

Background: The seasonal influenza vaccine is less effective in older people and a single dose is unlikely to provide the year-round protection necessary for tropical climates which have year-round influenza virus activity. This study aims to assess the effect of a trivalent inactivated influenza va...