Plasma-derived extracellular vesicles contain predictive biomarkers and potential therapeutic targets for myocardial ischemic (MI) injury

• Main Authors: Cheow, Esther Sok Hwee, Cheng, Woo Chin, Lee, Chuen Neng, de Kleijn, Dominique, Sorokin, Vitaly, Sze, Siu Kwan
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2018
• Subjects: Apolipoprotein; Clusterin; DRNTU::Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/80432; http://hdl.handle.net/10220/46550
• Institution: Nanyang Technological University

Myocardial infarction (MI) triggers a potent inflammatory response via the release of circulatory mediators, including extracellular vesicles (EVs) by damaged cardiac cells, necessary for myocardial healing. Timely repression of inflammatory response are critical to prevent and minimize cardiac tiss...