Characterization of the plasmodium interspersed repeats (PIR) proteins of plasmodium chabaudi indicates functional diversity

• Main Authors: Yam, Xue Yan, Brugat, Thibaut, Siau, Anthony, Lawton, Jennifer, Wong, Daniel S., Farah, Abdirahman, Twang, Jing Shun, Gao, Xiaohong, Langhorne, Jean, Preiser, Peter Rainer
• 其他作者: School of Biological Sciences
• 格式: Article
• 語言: English
• 出版: 2018
• 主題: Parasitology; Plasmodium Chabaudi; DRNTU::Science::Biological sciences
• 在線閱讀: https://hdl.handle.net/10356/80461; http://hdl.handle.net/10220/46517
• 機構: Nanyang Technological University

Plasmodium multigene families play a central role in the pathogenesis of malaria. The Plasmodium interspersed repeat (pir) genes comprise the largest multigene family in many Plasmodium spp. However their function(s) remains unknown. Using the rodent model of malaria, Plasmodium chabaudi, we show th...