Novel Photochrome Aptamer Switch Assay (PHASA) for Adaptive Binding to Aptamers

• Main Authors: Papper, Vladislav, Pokholenko, Oleksandr, Wu, Yuanyuan, Zhou, Yubin, Ping, Jianfeng, Steele, Terry W. J., Marks, Robert S.
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2017
• Subjects: Stilbene; Aptamer
• Online Access: https://hdl.handle.net/10356/80592; http://hdl.handle.net/10220/42178
• Institution: Nanyang Technological University

A novel Photochrome-Aptamer Switch Assay (PHASA) for the detection and quantification of small environmentally important molecules such as toxins, explosives, drugs and pollutants, which are difficult to detect using antibodies-based assays with high sensitivity and specificity, has been developed....