Continuous time Bayesian networks identify Prdm1 as a negative regulator of TH17 cell differentiation in humans

T helper 17 (TH17) cells represent a pivotal adaptive cell subset involved in multiple immune disorders in mammalian species. Deciphering the molecular interactions regulating TH17 cell differentiation is particularly critical for novel drug target discovery designed to control maladaptive inflammat...

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Bibliographic Details
Main Authors: Acerbi, Enzo, Viganò, Elena, Poidinger, Michael, Mortellaro, Alessandra, Zelante, Teresa, Stella, Fabio
Other Authors: Singapore Centre for Environmental Life Sciences Engineering
Format: Article
Language:English
Published: 2018
Subjects:
Online Access:https://hdl.handle.net/10356/80635
http://hdl.handle.net/10220/46573
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Institution: Nanyang Technological University
Language: English