Highly Fluorescent Polycaprolactones with Tunable Light Emission Wavelengths across Visible to NIR Spectral Window
Polycaprolactone (PCL) has been widely used in biomedical applications such as tissue engineering due to its promising biodegradability, biocompatibility, and mechanical processability. However, commercially available PCL without any fluorescence does not meet the increasing demand in biomedical app...
Saved in:
Main Authors: | , , , , |
---|---|
Other Authors: | |
Format: | Article |
Language: | English |
Published: |
2017
|
Subjects: | |
Online Access: | https://hdl.handle.net/10356/80749 http://hdl.handle.net/10220/43431 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Institution: | Nanyang Technological University |
Language: | English |
id |
sg-ntu-dr.10356-80749 |
---|---|
record_format |
dspace |
spelling |
sg-ntu-dr.10356-807492023-12-29T06:50:14Z Highly Fluorescent Polycaprolactones with Tunable Light Emission Wavelengths across Visible to NIR Spectral Window Huang, Shuo Wang, Kai Wang, Shipan Wang, Yue Wang, Mingfeng School of Chemical and Biomedical Engineering Biopolymers Dyes/pigments Polycaprolactone (PCL) has been widely used in biomedical applications such as tissue engineering due to its promising biodegradability, biocompatibility, and mechanical processability. However, commercially available PCL without any fluorescence does not meet the increasing demand in biomedical applications, for example, to monitor noninvasively the fate of implanted scaffolds in tissue engineering. To that end, exploration of new fluorescent PCL polymers plays an essential role in tracking their degradation under physiological conditions and distinguishing PCL scaffolds at the interface with biological systems such as cells and tissues. Herein, this study reports a series of tailor-made fluorescent PCL polymers with various light emission wavelengths ranging from visible to near-infrared (NIR) region in solid states. These fluorescent PCL polymers are amenable to be processed into nanofibers using electrospinning, as well as waterborne nanoparticle ink for macroscale stamping, brush writing, and microcontact printing. Finally, the application of the NIR fluorescent PCL for in vitro imaging and monitoring of scaffold degradation is demonstrated. MOE (Min. of Education, S’pore) Accepted version 2017-07-25T04:42:06Z 2019-12-06T13:58:07Z 2017-07-25T04:42:06Z 2019-12-06T13:58:07Z 2016 Journal Article Huang, S., Wang, K., Wang, S., Wang, Y., & Wang, M. (2016). Highly Fluorescent Polycaprolactones with Tunable Light Emission Wavelengths across Visible to NIR Spectral Window. Advanced Materials Interfaces, 3(17), 1600259-. https://hdl.handle.net/10356/80749 http://hdl.handle.net/10220/43431 10.1002/admi.201600259 en Advanced Materials Interfaces © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. This is the author created version of a work that has been peer reviewed and accepted for publication by Advanced Materials Interfaces, WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [http://dx.doi.org/10.1002/admi.201600259]. 15 p. application/pdf |
institution |
Nanyang Technological University |
building |
NTU Library |
continent |
Asia |
country |
Singapore Singapore |
content_provider |
NTU Library |
collection |
DR-NTU |
language |
English |
topic |
Biopolymers Dyes/pigments |
spellingShingle |
Biopolymers Dyes/pigments Huang, Shuo Wang, Kai Wang, Shipan Wang, Yue Wang, Mingfeng Highly Fluorescent Polycaprolactones with Tunable Light Emission Wavelengths across Visible to NIR Spectral Window |
description |
Polycaprolactone (PCL) has been widely used in biomedical applications such as tissue engineering due to its promising biodegradability, biocompatibility, and mechanical processability. However, commercially available PCL without any fluorescence does not meet the increasing demand in biomedical applications, for example, to monitor noninvasively the fate of implanted scaffolds in tissue engineering. To that end, exploration of new fluorescent PCL polymers plays an essential role in tracking their degradation under physiological conditions and distinguishing PCL scaffolds at the interface with biological systems such as cells and tissues. Herein, this study reports a series of tailor-made fluorescent PCL polymers with various light emission wavelengths ranging from visible to near-infrared (NIR) region in solid states. These fluorescent PCL polymers are amenable to be processed into nanofibers using electrospinning, as well as waterborne nanoparticle ink for macroscale stamping, brush writing, and microcontact printing. Finally, the application of the NIR fluorescent PCL for in vitro imaging and monitoring of scaffold degradation is demonstrated. |
author2 |
School of Chemical and Biomedical Engineering |
author_facet |
School of Chemical and Biomedical Engineering Huang, Shuo Wang, Kai Wang, Shipan Wang, Yue Wang, Mingfeng |
format |
Article |
author |
Huang, Shuo Wang, Kai Wang, Shipan Wang, Yue Wang, Mingfeng |
author_sort |
Huang, Shuo |
title |
Highly Fluorescent Polycaprolactones with Tunable Light Emission Wavelengths across Visible to NIR Spectral Window |
title_short |
Highly Fluorescent Polycaprolactones with Tunable Light Emission Wavelengths across Visible to NIR Spectral Window |
title_full |
Highly Fluorescent Polycaprolactones with Tunable Light Emission Wavelengths across Visible to NIR Spectral Window |
title_fullStr |
Highly Fluorescent Polycaprolactones with Tunable Light Emission Wavelengths across Visible to NIR Spectral Window |
title_full_unstemmed |
Highly Fluorescent Polycaprolactones with Tunable Light Emission Wavelengths across Visible to NIR Spectral Window |
title_sort |
highly fluorescent polycaprolactones with tunable light emission wavelengths across visible to nir spectral window |
publishDate |
2017 |
url |
https://hdl.handle.net/10356/80749 http://hdl.handle.net/10220/43431 |
_version_ |
1787136660938424320 |