DNA damage regulation and its role in drug-related phenotypes in the malaria parasites

• Main Authors: Gupta, Devendra Kumar, Patra, Alok Tanala, Zhu, Lei, Gupta, Archana Patkar, Bozdech, Zbynek
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2018
• Subjects: DNA Repair; DRNTU::Science::Biological sciences; DNA Damage
• Online Access: https://hdl.handle.net/10356/80806; http://hdl.handle.net/10220/46602
• Institution: Nanyang Technological University

DNA of malaria parasites, Plasmodium falciparum, is subjected to extraordinary high levels of genotoxic insults during its complex life cycle within both the mosquito and human host. Accordingly, most of the components of DNA repair machinery are conserved in the parasite genome. Here, we investigat...