Anti-Markovnikov hydroimination of terminal alkynes in gold-catalyzed pyridine construction from ammonia

Gold-catalyzed hydroimination of terminal alkynes, giving rise to anti-Markovnikov adducts concomitant with unstable Markovnikov adducts is described. The elementary step can be applied for the construction of pyridine derivatives from ammonia and alkynes.

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Bibliographic Details
Main Authors: Wang, Liliang, Kong, Lingbing, Li, Yongxin, Ganguly, Rakesh, Kinjo, Rei
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2015
Subjects:
Online Access:https://hdl.handle.net/10356/80851
http://hdl.handle.net/10220/38840
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Institution: Nanyang Technological University
Language: English
Description
Summary:Gold-catalyzed hydroimination of terminal alkynes, giving rise to anti-Markovnikov adducts concomitant with unstable Markovnikov adducts is described. The elementary step can be applied for the construction of pyridine derivatives from ammonia and alkynes.