From endosomes to the trans-Golgi network
The retrograde trafficking from endosomes to the trans-Golgi network (TGN) is one of the major endocytic pathways to divert proteins and lipids away from lysosomal degradation. Retrograde transported cargos enter the TGN via two itineraries from either the early endosome/recycling endosome or the la...
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sg-ntu-dr.10356-809162023-02-28T16:58:32Z From endosomes to the trans-Golgi network Lu, Lei Hong, Wanjin School of Biological Sciences Retromer Endosome Retrograde membrane trafficking Trans-Golgi network The retrograde trafficking from endosomes to the trans-Golgi network (TGN) is one of the major endocytic pathways to divert proteins and lipids away from lysosomal degradation. Retrograde transported cargos enter the TGN via two itineraries from either the early endosome/recycling endosome or the late endosome and involve various machinery components such as retromer, sorting nexins, clathrin, small GTPases, tethering factors and SNAREs. Recently, the pathway has been recognized for its role in signal transduction, physiology and pathogenesis of human diseases. NMRC (Natl Medical Research Council, S’pore) Accepted version 2015-12-02T08:38:17Z 2019-12-06T14:17:20Z 2015-12-02T08:38:17Z 2019-12-06T14:17:20Z 2014 Journal Article Lu, L., & Hong, W. (2014). From endosomes to the trans-Golgi network. Seminars in Cell & Developmental Biology, 31, 30-39. 1084-9521 https://hdl.handle.net/10356/80916 http://hdl.handle.net/10220/38899 10.1016/j.semcdb.2014.04.024 en Seminars in Cell & Developmental Biology © 2014 Elsevier Ltd. This is the author created version of a work that has been peer reviewed and accepted for publication by Seminars in Cell & Developmental Biology, Elsevier Ltd. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [http://dx.doi.org/10.1016/j.semcdb.2014.04.024]. 23 p. application/pdf |
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Retromer Endosome Retrograde membrane trafficking Trans-Golgi network |
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Retromer Endosome Retrograde membrane trafficking Trans-Golgi network Lu, Lei Hong, Wanjin From endosomes to the trans-Golgi network |
| description |
The retrograde trafficking from endosomes to the trans-Golgi network (TGN) is one of the major endocytic pathways to divert proteins and lipids away from lysosomal degradation. Retrograde transported cargos enter the TGN via two itineraries from either the early endosome/recycling endosome or the late endosome and involve various machinery components such as retromer, sorting nexins, clathrin, small GTPases, tethering factors and SNAREs. Recently, the pathway has been recognized for its role in signal transduction, physiology and pathogenesis of human diseases. |
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School of Biological Sciences |
| author_facet |
School of Biological Sciences Lu, Lei Hong, Wanjin |
| format |
Article |
| author |
Lu, Lei Hong, Wanjin |
| author_sort |
Lu, Lei |
| title |
From endosomes to the trans-Golgi network |
| title_short |
From endosomes to the trans-Golgi network |
| title_full |
From endosomes to the trans-Golgi network |
| title_fullStr |
From endosomes to the trans-Golgi network |
| title_full_unstemmed |
From endosomes to the trans-Golgi network |
| title_sort |
from endosomes to the trans-golgi network |
| publishDate |
2015 |
| url |
https://hdl.handle.net/10356/80916 http://hdl.handle.net/10220/38899 |
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1759856094335729664 |