Rupture of zwitterionic lipid vesicles by an amphipathic, α-helical peptide: Indirect effects of sensor surface and implications for experimental analysis

• Main Authors: Zan, Goh Haw, Cho, Nam-Joon
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2016
• Subjects: Quartz crystal microbalance-dissipation (QCM-D); Vesicle; Peptide; Lipid bilayer; Ellipsometry
• Online Access: https://hdl.handle.net/10356/80941; http://hdl.handle.net/10220/40630
• Institution: Nanyang Technological University

Surface-based measurement approaches offer competitive advantages for studying lipid membranes and membrane-active drug candidates. Continued development of surface-based membrane assays for pharmaceutical and biotechnology applications should account for physicochemical properties of the sensor sur...