Layering genetic circuits to build a single cell, bacterial half adder

• Main Authors: Wong, Adison, Wang, Huijuan, Poh, Chueh Loo, Kitney, Richard I.
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2015
• Online Access: https://hdl.handle.net/10356/80944; http://hdl.handle.net/10220/38986
• Institution: Nanyang Technological University

Background: Gene regulation in biological systems is impacted by the cellular and genetic context-dependent effects of the biological parts which comprise the circuit. Here, we have sought to elucidate the limitations of engineering biology from an architectural point of view, with the aim of compil...