Genome-Wide Screen Reveals Valosin-Containing Protein Requirement for Coronavirus Exit from Endosomes

• Main Authors: Wong, Hui Hui, Kumar, Pankaj, Tay, Felicia Pei Ling, Moreau, Dimitri, Liu, Ding Xiang, Bard, Frédéric
• Other Authors: Perlman, S.
• Format: Article
• Language: English
• Published: 2015
• Online Access: https://hdl.handle.net/10356/80970; http://hdl.handle.net/10220/38942
• Institution: Nanyang Technological University

Coronaviruses are RNA viruses with a large zoonotic reservoir and propensity for host switching, representing a real threat for public health, as evidenced by severe acute respiratory syndrome (SARS) and the emerging Middle East respiratory syndrome (MERS). Cellular factors required for their replic...