Molecular difference between WASP and N-WASP critical for chemotaxis of T-cells towards SDF-1α

Wiskott-Aldrich Syndrome protein (WASP) integrates cell signaling pathways to the actin cytoskeleton, which play a critical role in T-cell activation and migration. Hematopoietic cells express both WASP and neural-WASP (N-WASP) which share similar domain structure, yet WASP deficiency causes Wiskott...

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Bibliographic Details
Main Authors: Jain, Neeraj, Thanabalu, Thirumaran
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2015
Online Access:https://hdl.handle.net/10356/81030
http://hdl.handle.net/10220/39051
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Institution: Nanyang Technological University
Language: English