Aβ1-25-Derived Sphingolipid-Domain Tracer Peptide SBD Interacts with Membrane Ganglioside Clusters via a Coil-Helix-Coil Motif

• المؤلفون الرئيسيون: Wang, Yaofeng, Kraut, Rachel, Mu, Yuguang
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2015
• الموضوعات: Sphingolipid binding domain; Lipid rafts; Molecular dynamics simulation
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/81043; http://hdl.handle.net/10220/39068

The Amyloid-β (Aβ)-derived, sphingolipid binding domain (SBD) peptide is a fluorescently tagged probe used to trace the diffusion behavior of sphingolipid-containing microdomains in cell membranes through binding to a constellation of glycosphingolipids, sphingomyelin, and cholesterol. However, the...