A preclinical evaluation of an autologous living hyaline-like cartilaginous graft for articular cartilage repair: a pilot study

• Main Authors: Peck, Yvonne, He, Pengfei, Chilla, Geetha Soujanya V. N., Poh, Chueh Loo, Wang, Dong-An
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2015
• Online Access: https://hdl.handle.net/10356/81060; http://hdl.handle.net/10220/39056
• Institution: Nanyang Technological University

In this pilot study, an autologous synthetic scaffold-free construct with hyaline quality, termed living hyaline cartilaginous graft (LhCG), was applied for treating cartilage lesions. Implantation of autologous LhCG was done at load-bearing regions of the knees in skeletally mature mini-pigs for 6...