Plasmonic Nanohole Sensor for Capturing Single Virus-Like Particles toward Virucidal Drug Evaluation

A plasmonic nanohole sensor for virus-like particle capture and virucidal drug evaluation is reported. Using a materials-selective surface functionalization scheme, passive immobilization of virus-like particles only within the nanoholes is achieved. The findings demonstrate that a low surface cover...

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Main Authors: Jackman, Joshua Alexander, Linardy, Eric, Yoo, Daehan, Seo, Jeongeun, Ng, Wei Beng, Klemme, Daniel J., Wittenberg, Nathan J., Oh, Sang-Hyun, Cho, Nam-Joon
Other Authors: School of Chemical and Biomedical Engineering
Format: Article
Language:English
Published: 2016
Subjects:
Online Access:https://hdl.handle.net/10356/81081
http://hdl.handle.net/10220/40647
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-810812020-06-01T10:21:17Z Plasmonic Nanohole Sensor for Capturing Single Virus-Like Particles toward Virucidal Drug Evaluation Jackman, Joshua Alexander Linardy, Eric Yoo, Daehan Seo, Jeongeun Ng, Wei Beng Klemme, Daniel J. Wittenberg, Nathan J. Oh, Sang-Hyun Cho, Nam-Joon School of Chemical and Biomedical Engineering School of Materials Science & Engineering Centre for Biomimetic Sensor Science Sensors Nanoholes arrays Peptides Plasmonics Viruses Biosensing Biosensors A plasmonic nanohole sensor for virus-like particle capture and virucidal drug evaluation is reported. Using a materials-selective surface functionalization scheme, passive immobilization of virus-like particles only within the nanoholes is achieved. The findings demonstrate that a low surface coverage of particles only inside the functionalized nanoholes significantly improves nanoplasmonic sensing performance over conventional nanohole arrays. NRF (Natl Research Foundation, S’pore) NMRC (Natl Medical Research Council, S’pore) 2016-06-09T04:57:24Z 2019-12-06T14:21:00Z 2016-06-09T04:57:24Z 2019-12-06T14:21:00Z 2015 Journal Article Jackman, J. A., Linardy, E., Yoo, D., Seo, J., Ng, W. B., Klemme, D. J., et al. (2016). Plasmonic Nanohole Sensor for Capturing Single Virus-Like Particles toward Virucidal Drug Evaluation. Small, 12(9), 1159-1166. 1613-6810 https://hdl.handle.net/10356/81081 http://hdl.handle.net/10220/40647 10.1002/smll.201501914 en Small © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
institution Nanyang Technological University
building NTU Library
country Singapore
collection DR-NTU
language English
topic Sensors
Nanoholes arrays
Peptides
Plasmonics
Viruses
Biosensing
Biosensors
spellingShingle Sensors
Nanoholes arrays
Peptides
Plasmonics
Viruses
Biosensing
Biosensors
Jackman, Joshua Alexander
Linardy, Eric
Yoo, Daehan
Seo, Jeongeun
Ng, Wei Beng
Klemme, Daniel J.
Wittenberg, Nathan J.
Oh, Sang-Hyun
Cho, Nam-Joon
Plasmonic Nanohole Sensor for Capturing Single Virus-Like Particles toward Virucidal Drug Evaluation
description A plasmonic nanohole sensor for virus-like particle capture and virucidal drug evaluation is reported. Using a materials-selective surface functionalization scheme, passive immobilization of virus-like particles only within the nanoholes is achieved. The findings demonstrate that a low surface coverage of particles only inside the functionalized nanoholes significantly improves nanoplasmonic sensing performance over conventional nanohole arrays.
author2 School of Chemical and Biomedical Engineering
author_facet School of Chemical and Biomedical Engineering
Jackman, Joshua Alexander
Linardy, Eric
Yoo, Daehan
Seo, Jeongeun
Ng, Wei Beng
Klemme, Daniel J.
Wittenberg, Nathan J.
Oh, Sang-Hyun
Cho, Nam-Joon
format Article
author Jackman, Joshua Alexander
Linardy, Eric
Yoo, Daehan
Seo, Jeongeun
Ng, Wei Beng
Klemme, Daniel J.
Wittenberg, Nathan J.
Oh, Sang-Hyun
Cho, Nam-Joon
author_sort Jackman, Joshua Alexander
title Plasmonic Nanohole Sensor for Capturing Single Virus-Like Particles toward Virucidal Drug Evaluation
title_short Plasmonic Nanohole Sensor for Capturing Single Virus-Like Particles toward Virucidal Drug Evaluation
title_full Plasmonic Nanohole Sensor for Capturing Single Virus-Like Particles toward Virucidal Drug Evaluation
title_fullStr Plasmonic Nanohole Sensor for Capturing Single Virus-Like Particles toward Virucidal Drug Evaluation
title_full_unstemmed Plasmonic Nanohole Sensor for Capturing Single Virus-Like Particles toward Virucidal Drug Evaluation
title_sort plasmonic nanohole sensor for capturing single virus-like particles toward virucidal drug evaluation
publishDate 2016
url https://hdl.handle.net/10356/81081
http://hdl.handle.net/10220/40647
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