Design and Construction of Artificial Extracellular Matrix (aECM) Proteins from Escherichia coli for Skin Tissue Engineering

• Main Authors: Low, Pearlie Si Jia, Tjin, Monica Suryana, Fong, Eileen
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2016
• Subjects: Elastin-like domains; Phase transition behavior; Protein purification; Issue 100; Genetic engineering; Protein expression; Cell-binding domain; Artificial extracellular matrix proteins; Inverse transition cycling; Bioengineering
• Online Access: https://hdl.handle.net/10356/81217; http://hdl.handle.net/10220/39788
• Institution: Nanyang Technological University

Recombinant technology is a versatile platform to create novel artificial proteins with tunable properties. For the last decade, many artificial proteins that have incorporated functional domains derived from nature (or created de novo) have been reported. In particular, artificial extracellular mat...