Roughness-Controlled Self-Assembly of Mannitol/LB Agar Microparticles by Polymorphic Transformation for Pulmonary Drug Delivery

• Main Authors: Zhang, Fengying, Ngoc, Nguyen Thi Quynh, Tay, Bao Hui, Mendyk, Aleksander, Shao, Yu-Hsuan, Lau, Raymond
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2016
• Subjects: image analysis; self-assembly; pulmonary delivery; polymorphic transformation; surface morphology; mannitol
• Online Access: https://hdl.handle.net/10356/81256; http://hdl.handle.net/10220/40724
• Institution: Nanyang Technological University

Novel roughness-controlled mannitol/LB Agar microparticles were synthesized by polymorphic transformation and self-assembly method using hexane as the polymorphic transformation reagent and spray-dried mannitol/LB Agar microparticles as the starting material. As-prepared microparticles were characte...