pIgR and PECAM-1 bind to pneumococcal adhesins RrgA and PspC mediating bacterial brain invasion

pIgR and PECAM-1 bind to pneumococcal adhesins RrgA and PspC mediating bacterial brain invasion

Streptococcus pneumoniae is the main cause of bacterial meningitis, a life-threating disease with a high case fatality rate despite treatment with antibiotics. Pneumococci cause meningitis by invading the blood and penetrating the blood–brain barrier (BBB). Using stimulated emission depletion (STED)...

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Bibliographic Details
Main Authors: Iovino, Federico, Engelen-Lee, Joo-Yeon, Brouwer, Matthijs, van de Beek, Diederik, van der Ende, Arie, Valls Seron, Merche, Mellroth, Peter, Muschiol, Sandra, Bergstrand, Jan, Widengren, Jerker, Henriques-Normark, Birgitta
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2017
Subjects:
Pneumococcal adhesins
Bacterial meningitis
Online Access:https://hdl.handle.net/10356/81456
http://hdl.handle.net/10220/43471
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/81456
http://hdl.handle.net/10220/43471

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