Sec71 functions as a GEF for the small GTPase Arf1 to govern dendrite pruning of Drosophila sensory neurons

• المؤلفون الرئيسيون: Wang, Yan, Zhang, Heng, Shi, Meng, Liou, Yih-Cherng, Lu, Lei, Yu, Fengwei
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2017
• الموضوعات: Pruning; Dendrite
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/81485; http://hdl.handle.net/10220/43488
• المؤسسة: Nanyang Technological University

Pruning, whereby neurons eliminate their excess neurites, is central for the maturation of the nervous system. In Drosophila, sensory neurons, ddaCs, selectively prune their larval dendrites without affecting their axons during metamorphosis. However, it is unknown whether the secretory pathway play...