Highly sensitive inference of time-delayed gene regulation by network deconvolution

• Main Authors: Chen, Haifen, Mundra, Piyushkumar A, Zhao, Li Na, Lin, Feng, Zheng, Jie
• Other Authors: School of Computer Science and Engineering
• Format: Article
• Language: English
• Published: 2016
• Subjects: GRN inference; time delay; cross-correlation; network deconvolution
• Online Access: https://hdl.handle.net/10356/81490; http://hdl.handle.net/10220/40824
• Institution: Nanyang Technological University

Background: Gene regulatory network (GRN) is a fundamental topic in systems biology. The dynamics of GRN can shed light on the cellular processes, which facilitates the understanding of the mechanisms of diseases when the processes are dysregulated. Accurate reconstruction of GRN could also provide...