Ceramides And Stress Signalling Intersect With Autophagic Defects In Neurodegenerative Drosophila blue cheese (bchs) Mutants

Sphingolipid metabolites are involved in the regulation of autophagy, a degradative recycling process that is required to prevent neuronal degeneration. Drosophila blue cheese mutants neurodegenerate due to perturbations in autophagic flux, and consequent accumulation of ubiquitinated aggregates. He...

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Main Authors: Papan, Cyrus, Osborne, Kathleen Amy, Torta, Federico, Shevchenko, Andrej, Schwudke, Dominik, Kraut, Rachel, Hebbar, Sarita, Sahoo, Ishtapran, Matysik, Artur, Garcia, Irene Argudo, Narayanaswamy, Pradeep, Fun, Xiu Hui, Wenk, Markus R
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2016
Subjects:
Online Access:https://hdl.handle.net/10356/81549
http://hdl.handle.net/10220/39562
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Institution: Nanyang Technological University
Language: English