Nanoparticle-assisted optical tethering of endosomes reveals the cooperative function of dyneins in retrograde axonal transport

• Main Authors: Cui, Bianxiao, Chowdary, Praveen D., Che, Daphne L., Kaplan, Luke, Chen, Ou, Pu, Kanyi, Bawendi, Moungi
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2016
• Subjects: Chemical and Biomedical Engineering
• Online Access: https://hdl.handle.net/10356/81584; http://hdl.handle.net/10220/39577
• Institution: Nanyang Technological University

Dynein-dependent transport of organelles from the axon terminals to the cell bodies is essential to the survival and function of neurons. However, quantitative knowledge of dyneins on axonal organelles and their collective function during this long-distance transport is lacking because current techn...