A post-transcriptional mechanism pacing expression of neural genes with precursor cell differentiation status

• Main Authors: Dai, Weijun, Li, Wencheng, Hoque, Mainul, Li, Zhuyun, Tian, Bin, Makeyev, Eugene V.
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2016
• Subjects: Biological sciences; Cell biology
• Online Access: https://hdl.handle.net/10356/81630; http://hdl.handle.net/10220/40929
• Institution: Nanyang Technological University

Nervous system (NS) development relies on coherent upregulation of extensive sets of genes in a precise spatiotemporal manner. How such transcriptome-wide effects are orchestrated at the molecular level remains an open question. Here we show that 3′-untranslated regions (3′ UTRs) of multiple neural...