Sense-antisense gene-pairs in breast cancer and associated pathological pathways

• Main Authors: Jenjaroenpun, Piroon, Kuznetsov, Vladimir A., Grinchuk, Oleg V., Yenamandra, Surya Pavan, Ow, Ghim Siong, Ivshina, Anna V., Motakis, Efthymios, Tang, Zhiqun, Yarmishyn, Aliaksandr A.
• Other Authors: School of Computer Engineering
• Format: Article
• Language: English
• Published: 2016
• Subjects: Computer Science and Engineering
• Online Access: https://hdl.handle.net/10356/81711; http://hdl.handle.net/10220/39664
• Institution: Nanyang Technological University

More than 30% of human protein-coding genes form hereditary complex genome architectures composed of sense-antisense (SA) gene pairs (SAGPs) transcribing their RNAs from both strands of a given locus. Such architectures represent important novel components of genome complexity contributing to gene e...