Membrane attack complex formation on a supported lipid bilayer: initial steps towards a CARPA predictor nanodevice

The rapid advance of nanomedicines and biologicals in pharmacotherapy gives increasing importance to a common adverse effect of these modern therapeutics: complement (C) activation-related pseudoallergy (CARPA). CARPA is a relatively frequent and potentially lethal acute immune toxicity of many intr...

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Bibliographic Details
Main Authors: Yorulmaz, Saziye, Tabaei, Seyed R., Kim, Myunghee, Seo, Jeongeun, Hunziker, Walter, Szebeni, János, Cho, Nam-Joon
Other Authors: School of Materials Science & Engineering
Format: Article
Language:English
Published: 2016
Subjects:
Online Access:https://hdl.handle.net/10356/81739
http://hdl.handle.net/10220/39613
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Institution: Nanyang Technological University
Language: English