Soluble expression and partial purification of recombinant human erythropoietin from E. coli

• Main Authors: Jeong, Taeck-Hyun, Son, Young-Jin, Ryu, Han-Bong, Koo, Bon-Kyung, Jeong, Seung-Mi, Hoang, Phuong, Do, Bich Hang, Song, Jung-A, Chong, Seon-Ha, Robinson, Robert Charles, Choe, Han
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2016
• Subjects: rhEpo; Escherichia coli expression system
• Online Access: https://hdl.handle.net/10356/81778; http://hdl.handle.net/10220/40978
• Institution: Nanyang Technological University

Human erythropoietin (hEpo) is an essential regulator of erythrocyte production that induces the division and differentiation of erythroid progenitor cells in the bone marrow into mature erythrocytes. It is widely used for the treatment of anemia resulting from chronic kidney disease, chemotherapy,...