Generation of novel monoclonal antibodies for the enrichment and characterization of human corneal endothelial cells (hCENC) necessary for the treatment of corneal endothelial blindness

• Main Authors: Ding, Vanessa, Chin, Angela, Peh, Gary, Mehta, Jodhbir Singh, Choo, Andre
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2016
• Subjects: Human corneal endothelial cells; ALCAM/CD166
• Online Access: https://hdl.handle.net/10356/81798; http://hdl.handle.net/10220/40962
• Institution: Nanyang Technological University

Corneal transplantation is the primary treatment option to restore vision for patients with corneal endothelial blindness. Although the success rate of treatment is high, limited availability of transplant grade corneas is a major obstacle. Tissue-engineered corneal endothelial grafts constructed us...