mAb806 binding to epidermal growth factor receptor: a computational study

The epidermal growth factor receptor (EGFR) is an important target in the treatment of cancer. A very potent antibody, mAb806, has been developed against overexpressed EGFR and was found to be particularly active in brain tumors. Structural studies reveal that it binds to an epitope on the extracell...

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Main Authors: Ng, Yao Zong, Kannan, Srinivasaraghavan, Lane, David P., Fuentes, Gloria, Verma, Chandra Shekhar
其他作者: School of Biological Sciences
格式: Article
語言:English
出版: 2016
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在線閱讀:https://hdl.handle.net/10356/81819
http://hdl.handle.net/10220/40979
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