mAb806 binding to epidermal growth factor receptor: a computational study

mAb806 binding to epidermal growth factor receptor: a computational study

The epidermal growth factor receptor (EGFR) is an important target in the treatment of cancer. A very potent antibody, mAb806, has been developed against overexpressed EGFR and was found to be particularly active in brain tumors. Structural studies reveal that it binds to an epitope on the extracell...

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Bibliographic Details
Main Authors: Ng, Yao Zong, Kannan, Srinivasaraghavan, Lane, David P., Fuentes, Gloria, Verma, Chandra Shekhar
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2016
Subjects:
EGFR
extracellular domain
Online Access:https://hdl.handle.net/10356/81819
http://hdl.handle.net/10220/40979
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/81819
http://hdl.handle.net/10220/40979

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