Steroid-Decorated Antibiotic Microparticles for Inhaled Anti-Infective Therapy

• Main Authors: Lee, Sie Huey, Teo, Jeanette, Heng, Desmond, Zhao, Yanli, Ng, Wai Kiong, Chan, Hak-Kim, Tan, Reginald B. H.
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2016
• Subjects: dry powder inhaler; community-acquired pneumonia (CAP); chronic obstructive pulmonary disease (COPD) ;corticosteroids; combinatorial therapy; spray drying; aerosols;pulmonary drug delivery; formulation; antiinfectives
• Online Access: https://hdl.handle.net/10356/81907; http://hdl.handle.net/10220/39686
• Institution: Nanyang Technological University

Despite advances in vaccination and antimicrobial therapy, community-acquired pneumonia (CAP) remains as a leading cause of morbidity and mortality worldwide. As the severity of CAP has been linked to the extent of inflammation in the body, adjunctive therapeutic measures aimed at modulating the imm...